Louisville Cardinals vs Wake Forest Demon Deacons predictions, Sep 26, 2026

Score, Highlights

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On September 26, 2026, the Louisville Cardinals will host the Wake Forest Demon Deacons in an intriguing NCAA College Football matchup. Both teams enter this contest with promising recent form, each securing victories in 2 of their last 3 outings.

The Cardinals have shown a potent offensive display, leveraging their home-field advantage to dictate the pace of the game. Their ability to move the ball effectively in the air, combined with a strong ground game, makes them a formidable opponent. Meanwhile, the Demon Deacons are no slouches themselves, adapting well to various defensive schemes and demonstrating resilience in tight contests.

Bookmakers have set the odds at 1.15 for the home team and 4.65 for the visitors, reflecting a strong belief in Louisville’s potential to secure a win. Based on these odds, the predicted final score stands at 36-22, suggesting an anticipated margin of victory favoring the Cardinals.

In conclusion, while the Cardinals appear favored, the outcome remains uncertain as the Demon Deacons could very well upset the expectations, making for an exciting matchup. As always, approach this contest with caution in mind.

This preview is generated with the Welcome.Bet AI Insights Engine, combining form data, betting odds, and semantic SEO optimization to deliver relevant match analysis for fans and bettors alike from 2026-09-20T13:52:03+00:00.

Louisville 80.4%

Wake Forest 19.6%

Prediction (the most likely score): 36:22

Outrights of NCAA College Football Louisville: 0.49% Wake Forest: 0.44%

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Betting Odds

	1	X	2
	1.17		4.87
	1.18		5
	1.17		4.6
	1.15		4.65
	1.14		4.5

Latest Results

19.09.26 Louisville Cardinals football – Southern Methodist Mustangs football – 41:31 11.09.26 Louisville Cardinals football – Villanova Wildcats football – 59:13 06.09.26 Ole Miss Rebels football – Louisville Cardinals football – 41:38 23.12.25 Louisville Cardinals football – Toledo Rockets football – 27:22 29.11.25 Louisville Cardinals football – Kentucky Wildcats football – 41:0

18.09.26 Wake Forest Demon Deacons football – Miami FL Hurricanes football – 20:33 12.09.26 Purdue Boilermakers football – Wake Forest Demon Deacons football – 36:38 OT 03.09.26 Wake Forest Demon Deacons football – Akron Zips football – 38:16 02.01.26 Mississippi State Bulldogs football – Wake Forest Demon Deacons football – 29:43 29.11.25 Duke Blue Devils football – Wake Forest Demon Deacons football – 49:32

Facts

In the last 5 head-to-head matches, Louisville won 3.

Wake Forest could enjoy a physical edge thanks to more rest days ahead of this match.

In this match, Louisville enters as the overwhelming favorite.

In the last 9 head-to-head meetings, Louisville has recorded 6 wins, 0 draws, and 3 losses, with a goal aggregate of 340:277 (averaging 37.8:30.8 goals per game).

Specifically in home fixtures for Louisville against this opponent, the record stands at 4 wins, 0 draws, and 1 loss, with 192:120 goals (averaging 38.4:24 per game).

Latest Head To Head

29.10.22 Louisville Cardinals football – Wake Forest Demon Deacons football – 48:21 02.10.21 Wake Forest Demon Deacons football – Louisville Cardinals football – 37:34 12.12.20 Louisville Cardinals football – Wake Forest Demon Deacons football – 45:21 12.10.19 Wake Forest Demon Deacons football – Louisville Cardinals football – 59:62 27.10.18 Louisville Cardinals football – Wake Forest Demon Deacons football – 35:56

Standings

NCAA College Football Outrights

1. Ohio State: 5.95 (7.48%)

2. Texas: 6.05 (7.35%)

3. Georgia: 6.75 (6.59%)

4. Notre Dame: 7.45 (5.97%)

5. Miami (FL): 7.7 (5.78%)

6. Indiana: 8.6 (5.17%)

7. LSU: 13.6 (3.27%)

8. Ole Miss: 18 (2.47%)

9. Virginia: 20 (2.22%)

10. Oregon: 22.4 (1.99%)

11. Alabama: 23.4 (1.9%)

12. Florida Gators: 30.8 (1.44%)

13. Texas Tech: 31.2 (1.43%)

14. USC Trojans: 33.2 (1.34%)

15. Tennessee: 34.2 (1.3%)

16. Louisiana-Lafayette: 50 (0.89%)

17. Delaware Fightin: 50 (0.89%)

18. Texas A&M: 52 (0.86%)

19. Oklahoma: 56 (0.79%)

20. Penn State: 59 (0.75%)

21. Michigan: 65 (0.68%)

22. Oregon State: 90 (0.49%)

23. Jacksonville State: 90 (0.49%)

24. Miami (Oh): 90 (0.49%)

25. Appalachian State Mountaineers: 90 (0.49%)

26. Texas State Bobcats: 90 (0.49%)

27. Fresno State: 90 (0.49%)

28. Louisville: 90 (0.49%)

29. Western Michigan: 90 (0.49%)

30. Tulsa: 90 (0.49%)

31. UTSA: 90 (0.49%)

32. Liberty Flames: 90 (0.49%)

33. Army: 90 (0.49%)

34. Toledo: 90 (0.49%)

35. Old Dominion Monarchs: 90 (0.49%)

36. North Dakota State: 90 (0.49%)

37. South Alabama: 91 (0.49%)

38. Arkansas State: 91 (0.49%)

39. Troy: 91 (0.49%)

40. Florida Atlantic: 91 (0.49%)

41. Marshall: 91 (0.49%)

42. Central Michigan: 91 (0.49%)

43. Air Force: 91 (0.49%)

44. Louisiana Tech: 91 (0.49%)

45. Southern Methodist: 91 (0.49%)

46. Coastal Carolina: 92 (0.48%)

47. Massachusetts: 92 (0.48%)

48. San Jose State: 92 (0.48%)

49. Temple: 92 (0.48%)

50. Pittsburgh: 92 (0.48%)

51. Middle Tennessee St: 93 (0.48%)

52. Georgia State Panthers: 96 (0.46%)

53. South Carolina: 96 (0.46%)

54. West Virginia: 96 (0.46%)

55. Clemson: 96 (0.46%)

56. California: 96 (0.46%)

57. Duke: 96 (0.46%)

58. Georgia Tech: 98 (0.45%)

59. Missouri: 98 (0.45%)

60. Brigham Young: 98 (0.45%)

61. Auburn: 98 (0.45%)

62. Utah: 98 (0.45%)

63. Colorado State Rams: 100 (0.44%)

64. Mississippi St.: 100 (0.44%)

65. North Carolina State: 100 (0.44%)

66. North Carolina: 100 (0.44%)

67. Washington Huskies: 100 (0.44%)

68. Rutgers: 100 (0.44%)

69. Iowa: 100 (0.44%)

70. Wake Forest: 100 (0.44%)

71. Delaware State: 100 (0.44%)

72. Arizona Wildcats: 100 (0.44%)

73. Marryland Terrapins: 100 (0.44%)

74. Houston: 105 (0.42%)

75. Kansas State: 110 (0.4%)

76. Rice: 115 (0.39%)

77. Florida State: 115 (0.39%)

78. Oklahoma State: 115 (0.39%)

79. Vanderbilt: 120 (0.37%)

80. Virginia Tech: 120 (0.37%)

81. East Carolina: 130 (0.34%)

82. Colorado Buffaloes: 130 (0.34%)

83. Memphis: 130 (0.34%)

84. San Diego State: 130 (0.34%)

85. South Florida: 130 (0.34%)

86. Washington State: 130 (0.34%)

87. Minnesota Golden Gophers: 130 (0.34%)

88. UCLA: 130 (0.34%)

89. Purdue: 130 (0.34%)

90. Cincinnati Bearcats: 130 (0.34%)

91. Wisconsin: 130 (0.34%)

92. Baylor: 130 (0.34%)

93. Arkansas: 130 (0.34%)

94. Iowa State: 130 (0.34%)

95. Boise State: 130 (0.34%)

96. Stanford: 130 (0.34%)

97. Connecticut: 130 (0.34%)

98. Navy: 130 (0.34%)

99. Nebraska: 130 (0.34%)

100. Boston College: 130 (0.34%)

101. Kansas: 130 (0.34%)

102. Michigan State: 130 (0.34%)

103. James Madison: 130 (0.34%)

104. Syracuse: 130 (0.34%)

105. North Texas: 130 (0.34%)

106. UNLV Rebels: 130 (0.34%)

107. TCU: 130 (0.34%)

108. Arizona State: 130 (0.34%)

109. Tulane: 130 (0.34%)

110. New Mexico: 130 (0.34%)

111. UCF: 130 (0.34%)

112. Illinois: 130 (0.34%)

113. Kentucky: 130 (0.34%)

114. Northwestern: 130 (0.34%)

115. Arizona: 200 (0.22%)

116. Maryland: 250 (0.18%)

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