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Pittsburgh Pirates vs St. Louis Cardinals predictions, Apr 28, 2026

Yuriy Borshchenko

MLB, PNC Park (Pittsburgh, PA) on Tuesday,

Score, Highlights

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On April 28, 2026, the Pittsburgh Pirates will host the St. Louis Cardinals in an exciting MLB showdown at PNC Park. This matchup pits two teams with varying recent fortunes against each other, with the Pirates securing victory in 2 of their last 5 games, while the Cardinals have struggled, managing just 1 win in their last 5 outings.

Bookmakers favor the Pirates with odds of 1.63 for a home win compared to the Cardinals’ 2.36 for an away victory. Our predictive model gives the Pirates a 58.7% chance of winning, highlighting their current form advantage. The recent performances suggest that the Pirates may capitalize on their home-field advantage, combining solid pitching with a resilient lineup that has the potential to exploit the Cardinals’ weaknesses.

Tactically, the Pirates’ offense has demonstrated the ability to score effectively, with a predicted final score of 5-3 reflecting their capacity to capitalize on scoring opportunities. While the Cardinals will aim to correct their trajectory and leverage their historical rivalry, their recent form may hamper their effectiveness.

As the game approaches, both teams will look to assert their strategies, making this matchup one to closely watch, though no outcome is guaranteed.

This preview is generated with the Welcome.Bet AI Insights Engine, combining form data, betting odds, and semantic SEO optimization to deliver relevant match analysis for fans and bettors alike from 2026-04-28T03:52:03+00:00.

Pittsburgh
59.1%		 St. Louis
40.9%

Prediction (the most likely score): 5:3

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Betting Odds

1 X 2
1.65 2.38
1.61 2.33
1.66 2.39
1.6 2.35

Latest Results

27.04.26 Pittsburgh Pirates – St. Louis Cardinals – 2:4
26.04.26 Milwaukee Brewers – Pittsburgh Pirates – 5:0
25.04.26 Milwaukee Brewers – Pittsburgh Pirates – 3:6
24.04.26 Milwaukee Brewers – Pittsburgh Pirates – 0:6
23.04.26 Texas Rangers – Pittsburgh Pirates – 6:1		 27.04.26 Pittsburgh Pirates – St. Louis Cardinals – 2:4
26.04.26 St. Louis Cardinals – Seattle Mariners – 2:3
25.04.26 St. Louis Cardinals – Seattle Mariners – 2:3
24.04.26 St. Louis Cardinals – Seattle Mariners – 2:3
22.04.26 Miami Marlins – St. Louis Cardinals – 4:1

Facts

  • Two mid-table teams will face off this time (ranked 7 and 8).
  • In the last 5 head-to-head matches, Pittsburgh won 2.
  • In recent matches, Pittsburgh has shown inconsistent form (last 5 games: 2 wins).
  • St. Louis is going through a rough patch (in the last 5 games, wins – 1).
  • Recently, Pittsburgh has had a series of away games.
  • Pittsburgh is expected to have a slight advantage in this match.
  • In the last 20 head-to-head matches, Pittsburgh won 9 matches, drew 0 matches, lost 11 matches, and goals 66:65. (average 3.3:3.3).
  • Including home matches between the teams, Pittsburgh won 5 matches, drew 0 matches, lost 3 matches, and goals 30:17. (average 3.8:2.1).

    Latest Head To Head

    27.04.26 Pittsburgh Pirates – St. Louis Cardinals – 2:4
    05.03.26 Pittsburgh Pirates – St. Louis Cardinals – 2:3
    01.03.26 St. Louis Cardinals – Pittsburgh Pirates – 1:6
    28.08.25 St. Louis Cardinals – Pittsburgh Pirates – 4:1
    27.08.25 St. Louis Cardinals – Pittsburgh Pirates – 1:2

    Standings

    Main

    American League

    Pl W L PCT
    1 New York Yankees 29 19 10 150:101 0.655
    2 Tampa Bay Rays 28 17 11 135:135 0.607
    3 Athletics 28 15 13 119:127 0.536
    4 Detroit Tigers 29 15 14 132:122 0.517
    5 Cleveland Guardians 30 15 15 120:129 0.500
    6 Texas Rangers 29 14 15 115:109 0.483
    7 Seattle Mariners 30 14 16 122:123 0.467
    8 Baltimore Orioles 28 13 15 125:140 0.464
    9 Minnesota Twins 29 13 16 143:136 0.448
    10 Toronto Blue Jays 28 12 16 110:138 0.429
    11 Chicago White Sox 29 12 17 121:149 0.414
    12 Boston Red Sox 29 12 17 122:128 0.414
    13 Los Angeles Angels 30 12 18 146:153 0.400
    14 Kansas City Royals 28 11 17 117:136 0.393
    15 Houston Astros 29 11 18 151:174 0.379

    National League

    Pl W L PCT
    1 Atlanta Braves 29 20 9 166:101 0.690
    2 Los Angeles Dodgers 29 20 9 164:96 0.690
    3 San Diego Padres 28 19 9 132:118 0.679
    4 Cincinnati Reds 28 18 10 118:117 0.643
    5 Chicago Cubs 29 17 12 156:127 0.586
    6 Arizona Diamondbacks 27 15 12 132:137 0.556
    7 Pittsburgh Pirates 29 16 13 137:115 0.552
    8 St.Louis Cardinals 28 15 13 129:142 0.536
    9 Milwaukee Brewers 27 14 13 132:113 0.519
    10 San Francisco Giants 28 13 15 97:114 0.464
    11 Washington Nationals 29 13 16 156:171 0.448
    12 Colorado Rockies 29 13 16 118:129 0.448
    13 Miami Marlins 29 13 16 130:131 0.448
    14 Philadelphia Phillies 28 9 19 102:156 0.321
    15 New York Mets 28 9 19 92:122 0.321

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