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San Lorenzo vs Santos predictions, Apr 28, 2026

Copa Sudamericana, on Tuesday,

Score, Highlights

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As the Copa Sudamericana approaches, San Lorenzo will host Santos FC on April 28, 2026, in what promises to be an intriguing matchup. Both teams have had mixed results in their recent outings, with San Lorenzo managing to secure two victories in their last five matches, while Santos has struggled, winning just once in the same period.

San Lorenzo’s home advantage may play a crucial role, especially given the bookmakers’ odds favoring them at 2.3 for a home win compared to 3.3 for Santos FC. The model predicts a 41.8% chance of a home victory, reflecting San Lorenzo’s solid defensive framework alongside an effective attack, which could prove decisive in this knockout stage.

Santos, on the other hand, will need to address their recent struggles to establish a cohesive gameplay strategy. Though their form has been inconsistent, they possess the capability to pull off an upset. The predicted final score of 1-0 underscores the expectation of a tightly contested match, likely depending on set-pieces or defensive errors.

In summary, while recent performances lean towards a San Lorenzo win, both teams are vying for a critical advantage, and surprises can occur in knockout competitions. As always, cautious betting is advised given the uncertainty inherent in sports results.

This preview is generated with the Welcome.Bet AI Insights Engine, combining form data, betting odds, and semantic SEO optimization to deliver relevant match analysis for fans and bettors alike from 2026-04-21T20:52:02+00:00.

San Lorenzo
40.5%
Draw
31.3%
Santos
28.2%

Prediction (the most likely score): 1:0

Outrights of Copa Sudamericana Santos: 4.27% San Lorenzo: 2.21%

Watch and Bet San Lorenzo – Santos available at: Bet Now (Full Screen)

Betting Odds

1 X 2
2.32 2.89 3.45
2.32 2.88 3.25
2.31 2.9 3.38 Watch and Bet
2.3 2.8 3.3
2.32 3.01 3.39

Latest Results

20.04.26 San Lorenzo – Vélez Sársfield – 0:0
16.04.26 San Lorenzo – Deportivo Cuenca – 2:0
12.04.26 Newells Old Boys – San Lorenzo – 0:0
08.04.26 Deportivo Recoleta – San Lorenzo – 1:1
03.04.26 San Lorenzo – Estudiantes La Plata – 1:0
19.04.26 Santos FC – Fluminense RJ – 2:3
14.04.26 Santos FC – Deportivo Recoleta – 1:1
11.04.26 Santos FC – Atlético Mineiro – 1:0
08.04.26 Deportivo Cuenca – Santos FC – 1:0
05.04.26 Flamengo RJ – Santos FC – 3:1

Facts

  • San Lorenzo is currently in amazing form (last 5 games: 2 wins).
  • Santos‘s performance has dropped in recent matches (in the last 5 games, wins – 1).
  • San Lorenzo might have a minor edge in this game.
  • In the last 2 head-to-head matches, San Lorenzo won 0 matches, drew 1 match, lost 1 match, and goals 3:5. (average 1.5:2.5).
  • Including home match between the teams, San Lorenzo won 0 matches, drew 0 matches, lost 1 match, and goals 1:3.

    Latest Head To Head

    13.04.21 Santos FC – San Lorenzo – 2:2
    06.04.21 San Lorenzo – Santos FC – 1:3

    Standings

    Group Stage

    Group A

    Pl W D L Diff Pts
    1 America De Cali 2 1 1 0 3:2 1 4
    2 Macara 2 1 1 0 2:1 1 4
    3 Alianza Atl 2 0 1 1 2:3 -1 1
    4 Tigre 2 0 1 1 1:2 -1 1

    Group B

    Pl W D L Diff Pts
    1 Cienciano 2 1 1 0 3:1 2 4
    2 Puerto Cabello 2 1 0 1 2:3 -1 3
    3 Atletico-MG 2 1 0 1 3:3 0 3
    4 Juventud 2 0 1 1 2:3 -1 1

    Group C

    Pl W D L Diff Pts
    1 Sao Paulo 2 2 0 0 3:0 3 6
    2 O’Higgins 2 1 0 1 2:2 0 3
    3 Millonarios 2 1 0 1 1:2 -1 3
    4 Boston River 2 0 0 2 0:2 -2 0

    Group D

    Pl W D L Diff Pts
    1 San Lorenzo 2 1 1 0 3:1 2 4
    2 Dep. Cuenca 2 1 0 1 1:2 -1 3
    3 Recoleta 2 0 2 0 2:2 0 2
    4 Santos 2 0 1 1 1:2 -1 1

    Group E

    Pl W D L Diff Pts
    1 Botafogo RJ 2 1 1 0 4:3 1 4
    2 Caracas 2 1 1 0 2:1 1 4
    3 Racing Club 2 1 0 1 5:4 1 3
    4 Independiente 2 0 0 2 1:4 -3 0

    Group F

    Pl W D L Diff Pts
    1 Montevideo City 2 2 0 0 3:0 3 6
    2 Gremio 2 1 0 1 1:1 0 3
    3 Dep. Riestra 2 0 1 1 0:1 -1 1
    4 Palestino 2 0 1 1 0:2 -2 1

    Group G

    Pl W D L Diff Pts
    1 Olimpia Asuncion 2 1 1 0 2:0 2 4
    2 A. Italiano 2 1 0 1 2:3 -1 3
    3 Barracas Central 2 0 2 0 0:0 0 2
    4 Vasco 2 0 1 1 1:2 -1 1

    Group H

    Pl W D L Diff Pts
    1 River Plate 2 1 1 0 2:1 1 4
    2 Carabobo 2 1 0 1 1:1 0 3
    3 Bragantino 2 1 0 1 3:3 0 3
    4 Blooming 2 0 1 1 3:4 -1 1

    Copa Sudamericana Outrights

    1. Atletico-MG: 6 (10.68%)

    2. Sao Paulo: 7 (9.15%)

    3. Racing Montevideo: 7 (9.15%)

    4. River Plate: 7 (9.15%)

    5. Racing Club: 7 (9.15%)

    6. Botafogo RJ: 8 (8.01%)

    7. Gremio: 10 (6.41%)

    8. Santos: 15 (4.27%)

    9. Vasco: 17 (3.77%)

    10. Bragantino: 17 (3.77%)

    11. America De Cali: 17 (3.77%)

    12. Olimpia Asuncion: 26 (2.46%)

    13. Olimpia: 26 (2.46%)

    14. San Lorenzo: 29 (2.21%)

    15. Montevideo City: 29 (2.21%)

    16. Millonarios: 29 (2.21%)

    17. Tigre: 50.2 (1.28%)

    18. A. Italiano: 50.2 (1.28%)

    19. Cienciano: 80.2 (0.8%)

    20. Dep. Cuenca: 80.2 (0.8%)

    21. O Higgins: 80.25 (0.8%)

    22. Palestino: 100.2 (0.64%)

    23. Barracas Central: 100.2 (0.64%)

    24. Macara: 110.2 (0.58%)

    25. Carabobo: 112.75 (0.57%)

    26. Juventud: 112.75 (0.57%)

    27. Deportivo Riestra: 120.2 (0.53%)

    28. Caracas: 120.2 (0.53%)

    29. Boston River: 180.2 (0.36%)

    30. Independiente: 180.2 (0.36%)

    31. Alianza Atl.: 180.2 (0.36%)

    32. Academia Puerto Cabello: 180.2 (0.36%)

    33. Recoleta: 180.2 (0.36%)

    34. Blooming: 180.2 (0.36%)

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