Atlético San Luis vs Santos Laguna predictions, Apr 22, 2026

Mexican Liga MX, on Wednesday,

Atlético San Luis

Santos Laguna

Score, Highlights

Short Preview

As Atlético San Luis prepares to host Santos Laguna on April 22, 2026, both teams are looking to improve their standings in the Mexican Liga MX. Recent form reveals Atlético San Luis struggling to find consistency, having secured only one victory in their last five matches. This could pose challenges as they encounter a Santos Laguna side that has managed to win two of their recent outings, suggesting a modest uptick in form.

In terms of tactical strengths, Atlético San Luis will need to leverage their home advantage to disrupt Santos Laguna’s rhythm. Their home ground typically plays a significant role in their performance, but a lack of defensive solidity in recent games has been concerning. On the other hand, Santos Laguna has shown a more balanced attack, with their ability to exploit counter-attacks potentially causing problems for the hosts.

Betting odds reflect these dynamics, favoring a home victory at 1.7, while Santos Laguna sits at 3.93. Model predictions indicate a 51.1% probability for a home win. While Atlético San Luis will be keen to capitalize on this match, each team’s recent form suggests that an unpredictable contest may unfold. As always, sports outcomes remain uncertain, making this a compelling matchup to watch.

This preview is generated with the Welcome.Bet AI Insights Engine, combining form data, betting odds, and semantic SEO optimization to deliver relevant match analysis for fans and bettors alike from 2026-04-16T04:52:03+00:00.

Atlético San Luis
53.2%
Draw
23.6%
Santos Laguna
23.2%

Prediction (the most likely score): 2:1

Outrights of Mexican Liga MX Santos Laguna: 0.18%

Watch Watch and Bet Atlético San Luis – Santos Laguna available at: Bet Now (Full Screen)

Betting Odds

1 X 2
betsson 1.78 3.95 3.95
MarathonBet 1.76 3.92 3.99 Watch Watch and Bet
WilliamHill 1.73 3.5 3.75
Pinnacle 1.74 4.18 4.09

Latest Results

12.04.26 Deportivo Toluca – Atlético San Luis – 1:1
04.04.26 CF Monterrey – Atlético San Luis – 1:2
21.03.26 Atlético San Luis – Club León – 1:2
14.03.26 Atlético San Luis – CF Pachuca – 1:1
07.03.26 Cruz Azul FC – Atlético San Luis – 3:0
11.04.26 CF Pachuca – Santos Laguna – 4:2
04.04.26 Santos Laguna – Club América – 1:1
22.03.26 Santos Laguna – Puebla FC – 2:1
14.03.26 Chivas Guadalajara – Santos Laguna – 3:0
08.03.26 Club Tijuana – Santos Laguna – 1:2

Facts

  • We will watch a tense game between outsiders (ranked 14 and 18).
  • In the last 5 head-to-head matches, Atlético San Luis won 4.
  • Both teams have been playing unpredictably.
  • In this match, Atlético San Luis is a strong favorite.
  • In the last 17 head-to-head matches, Atlético San Luis won 6 matches, drew 4 matches, lost 7 matches, and goals 23:25. (average 1.4:1.5).
  • Including home matches between the teams, Atlético San Luis won 3 matches, drew 2 matches, lost 3 matches, and goals 11:11. (average 1.4:1.4).

    Latest Head To Head

    21.09.25 Santos Laguna – Atlético San Luis – 1:4
    30.03.25 Santos Laguna – Atlético San Luis – 2:3
    28.09.24 Atlético San Luis – Santos Laguna – 3:1
    28.04.24 Santos Laguna – Atlético San Luis – 0:3
    11.11.23 Atlético San Luis – Santos Laguna – 0:2

    Standings

    Clausura

    Pl W D L Diff Pts
    1 Guadalajara Chivas ✔ 14 10 1 3 28:17 11 31
    2 Cruz Azul 14 8 4 2 25:15 10 28
    3 Pachuca 14 8 4 2 21:13 8 28
    4 UNAM Pumas 14 7 6 1 26:15 11 27
    5 Toluca 14 7 6 1 20:9 11 27
    6 Tigres UANL 14 6 2 6 22:16 6 20
    7 Club America 14 5 4 5 15:13 2 19
    8 Atlas 14 5 4 5 14:18 -4 19
    9 Club Leon 14 6 1 7 16:24 -8 19
    10 Club Tijuana 14 4 6 4 15:15 0 18
    11 Juarez 14 4 4 6 21:24 -3 16
    12 Necaxa 14 5 1 8 17:20 -3 16
    13 Monterrey 14 4 3 7 19:17 2 15
    14 Atl. San Luis 14 4 3 7 21:23 -2 15
    15 Queretaro 14 3 6 5 13:18 -5 15
    16 Puebla 14 3 4 7 11:17 -6 13
    17 Mazatlan FC 14 3 2 9 16:28 -12 11
    18 Santos Laguna 14 2 3 9 17:35 -18 9

    Mexican Liga MX Outrights

    1. Cruz Azul: 4.5 (20.23%)

    2. Toluca: 5 (18.2%)

    3. Pachuca: 9 (10.11%)

    4. Guadalajara: 9.5 (9.58%)

    5. UNAM Pumas: 10 (9.1%)

    6. Club America: 11 (8.27%)

    7. Tigres UANL: 13 (7%)

    8. Monterrey: 26 (3.5%)

    9. Atlas: 26 (3.5%)

    10. Club Leon: 34 (2.68%)

    11. Necaxa: 41 (2.22%)

    12. Club Tijuana: 41 (2.22%)

    13. Juarez: 67 (1.36%)

    14. Atletico San Luis: 101 (0.9%)

    15. Queretaro: 201 (0.45%)

    16. Mazatlan FC: 301 (0.3%)

    17. Santos Laguna: 501 (0.18%)

    18. Puebla: 501 (0.18%)

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